An oestradiol blood test, also known as an estradiol assay or E2 test, measures the levels of estradiol in the blood. Oestradiol is the primary female sex hormone and is one of the three major forms of estrogen. It plays a vital role in the menstrual cycle, reproductive health, and various physiological processes in both females and males.

The oestradiol blood test is commonly ordered in the following situations:

  1. Assessing fertility: Oestradiol levels are measured during the menstrual cycle to evaluate ovarian function and determine the appropriate timing for procedures like in vitro fertilization (IVF).
  2. Evaluating menstrual irregularities: Abnormal levels of oestradiol may contribute to menstrual irregularities, such as absent or irregular periods and can help identify potential causes.
  3. Monitoring hormone replacement therapy (HRT): In menopausal women or individuals undergoing hormone replacement therapy, oestradiol levels are monitored to ensure the appropriate dosage and effectiveness of treatment.
  4. Evaluating symptoms of hormonal imbalance: Symptoms such as hot flashes, mood changes, vaginal dryness, or decreased libido may prompt a healthcare provider to order an oestradiol test to assess hormonal status.
  5. Assessing precocious puberty or delayed puberty: Oestradiol levels can help evaluate the development of secondary sexual characteristics in children.

The timing of the oestradiol test is crucial, especially for menstrual cycle-related assessments. In premenopausal women, the test is typically performed on specific days of the menstrual cycle, such as the early follicular phase (days 2-4), mid-cycle (around day 14 during ovulation), or the luteal phase (after ovulation). Your healthcare provider will advise you on the appropriate timing for testing based on your specific situation.

Interpretation of oestradiol levels can vary depending on the purpose of the test, age, and sex. It’s important to consult a healthcare professional who can evaluate your test results in the context of your symptoms and medical history.

Please note that this information is not a substitute for professional medical advice and it’s always best to consult a healthcare provider for personalised guidance and interpretation of test results.