Ureaplasma is a type of bacteria that can infect the urinary and reproductive systems. There are two species of Ureaplasma that commonly affect humans: Ureaplasma parvum and Ureaplasma urealyticum.


Ureaplasma can be transmitted through sexual contact, but it can also be found naturally in the genital tract of some individuals without causing symptoms. It can be passed between sexual partners.


Ureaplasma infections are often asymptomatic, meaning many people infected with Ureaplasma may not experience any noticeable symptoms. When symptoms do occur, they can vary depending on the affected area. In males, symptoms may include urethritis (inflammation of the urethra) with symptoms like burning or discomfort during urination. In females, symptoms may include urinary tract infection (UTI)-like symptoms, vaginal discharge, or pelvic pain.


Ureaplasma infections are diagnosed through laboratory testing. A healthcare professional may collect a sample of urine, vaginal fluid, or discharge for analysis. Ureaplasma can be detected using techniques like polymerase chain reaction (PCR) or culture. It’s important to note that the presence of Ureaplasma alone does not necessarily indicate an active infection, as it can be present without causing symptoms or harm.


Treatment for Ureaplasma infections may be recommended in certain cases, particularly if symptoms are present or if the infection is causing complications. However, treatment decisions are made on a case-by-case basis, taking into consideration factors such as symptoms, clinical history, and the presence of other infections. Antibiotics like azithromycin or doxycycline are commonly prescribed to treat Ureaplasma infections.

Testing for Ureaplasma infections typically involves laboratory tests that can detect the presence of the bacteria. Here are the common tests used for diagnosing Ureaplasma:

  1. Nucleic acid amplification tests (NAATs): NAATs are highly sensitive and specific tests that detect the genetic material (DNA or RNA) of Ureaplasma bacteria. A sample of urine, vaginal fluid, or discharge is collected and analyzed using techniques like polymerase chain reaction (PCR) or transcription-mediated amplification (TMA). NAATs can identify the presence of Ureaplasma species and determine the specific type, such as Ureaplasma parvum or Ureaplasma urealyticum.
  2. Culture: Ureaplasma can also be cultured in the laboratory, although it may require specific culture media and conditions. A sample of vaginal fluid, discharge, or urine is collected and inoculated onto a culture plate. The bacteria are allowed to grow, and their presence is confirmed by observing characteristic growth patterns. However, culture methods may take longer and may not be as sensitive as NAATs for detecting low levels of Ureaplasma.

It’s important to note that testing for Ureaplasma may not be a routine part of standard STI screenings. Therefore, if you suspect a Ureaplasma infection or have been experiencing symptoms, it’s best to discuss your concerns with a healthcare professional. They can evaluate your symptoms, perform the necessary tests, and provide appropriate treatment recommendations if needed.

It’s also worth mentioning that the presence of Ureaplasma does not always indicate an active infection or require treatment. Asymptomatic individuals may have Ureaplasma colonisation without experiencing any harm or requiring treatment. The decision to treat Ureaplasma infections is typically based on the presence of symptoms, clinical evaluation, and consideration of other factors. Consulting with a healthcare professional is crucial for proper diagnosis and management of Ureaplasma infections.